Saturday, February 23, 2013

Cut Commitments, Not Muscle

In that year of happy memory, 1972, George McGovern, the Democratic nominee, declared he would chop defense by fully one-third.

A friendly congressman was persuaded to ask Secretary of Defense Melvin Laird to expatiate on what this might mean.

The Pentagon replied the Sixth Fleet might have to be pulled out of the Med, leaving Israel without U.S. protection against the fleet of Adm. Sergei Gorshkov, and provided the congressman a list of U.S. bases that would have to be shut down.

Radio ads were run in the towns closest to the bases on the Pentagon list, declaring they would be closed and all jobs terminated, should McGovern win.

Something akin to this is going on with the impending sequester.

A cut of 7 percent, $46 billion, in Pentagon spending, says Army chief Ray Odierno, will mean a "hollowing" out of his force.

The Navy? The carrier Harry Truman will not be sailing to the Persian Gulf. The Abraham Lincoln will not be overhauled in Newport News. Thousands of jobs will be lost.

Reporter Rowan Scarborough writes that the Air Force has produced "a map of the U.S. that shows state-by-state the millions of dollars lost to local economies," should the guillotine fall.

Military aid to Israel may be cut, says John Kerry.

But if an evisceration of the national defense is imminent, why did Obama not tell us in 2012? Why were the joint chiefs silent, when they are panicked now? Are the generals, admirals and contractors all crying wolf?

Undeniably, spending cuts by sequester slicer, chopping all equally, is mindless. And with the national security, it manifests a failure of both parties to come to terms with the world we are now in.

The Cold War is over. The Soviet Union is gone. Mao's China is gone, though a mightier China has emerged, as America's share of the global economy is shrinking. Moreover, as ex-Chairman of the Joint Chiefs Mike Mullen contends, our greatest strategic threat is not Kim Jong Un or Mahmoud Ahmadinejad, but the soaring national debt.

And if, as Republicans insist, we have a debt crisis because we are "spending too much," spending will have to be cut ? discretionary spending, entitlements and defense. And the only question about the defense cuts is not whether they are coming, but where.

What is needed is what America, since the collapse of the Soviet Empire, has stubbornly resisted doing: a strategic review of all U.S. commitments abroad to determine which remain vital to the national security. Before we decide what our defense forces should be, let us determine what is in the U.S. vital interest to defend at risk of war.

Start with NATO. In 1961, President Eisenhower urged JFK to bring home the U.S. forces and let the Europeans raise the armies to defend themselves, lest they become military dependencies.

Yet, more than 20 years after the Wall fell, the Red Army went home, East Europe broke free and the Soviet Union fell apart, we have scores of thousands of troops in Europe.

Why? The European Union's economy is 10 times that of Russia. Europe's population is twice Russia's.

Why are we still there?

Though we have given NATO war guarantees to Lithuania, Latvia and Estonia, our McCainiacs want them handed out to the Ukraine and Georgia. Yet no president in his right mind is going to go to war with a nuclear-armed Russia over some Caucasus dustup or Baltic brawl.

If Richard Nixon could achieve a modus vivendi with Chairman Mao, have we no statesman who can patch it up with Vladimir Putin? A first step might be to pull all U.S. missiles out of Eastern Europe and put our democracy-meddlers on the next plane out of Moscow.

Even as Ike was telling JFK to bring the troops home from Europe, Gen. Douglas MacArthur was urging JFK not to put his foot soldiers in Asia ? advice not taken there, either.

On retirement, Robert Gates said any future defense secretary who advises a president to fight another land war in Asia ought to have his head examined. So why do we have 28,000 U.S. troops in Korea and 50,000 in Japan?

In his Guam Doctrine, Nixon declared that in any future Asian war, we should provide the weapons to our Asian allies and they should do the fighting. Does that not still make sense today? Before we can decide the size and shape of our defense budget, we need a consensus on what we must defend.

And if Republicans wish to remain a viable party, they cannot delegate these decisions to the "We-are-all-Georgians-now!" crowd that plunged us into Iraq and is bawling for intervention in Syria and war on Iran.

The GOP desperately needs a credible, countervailing voice to the uber-hawks whose bellicosity all but killed the party in the Bush era.

Obama is president because of them. And his most popular act, according to voter surveys from 2012? Ending the war in Iraq.

Patrick J. Buchanan is the author of "Suicide of a Superpower: Will America Survive to 2025?" To find out more about Patrick Buchanan and read features by other Creators Syndicate writers and cartoonists, visit the Creators Syndicate webpage at www.creators.com.

COPYRIGHT 2013 CREATORS.COM

Source: http://news.yahoo.com/cut-commitments-not-muscle-080000844.html

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NFL Draft order as it currently stands

?The NFL has released the tentative round-by-round order for the 2013 NFL Draft.?

?Note that the order does not include compensatory selections, which will be awarded at the bottom of Rounds 3-7 and announced next month.

?

Round

Pick

Overall

1

1

1

Kansas City

1

2

2

Jacksonville

1

3

3

Oakland

1

4

4

Philadelphia

1

5

5

Detroit

1

6

6

Cleveland

1

7

7

Arizona

1

8

8

Buffalo

1

9

9

New York Jets

1

10

10

Tennessee

1

11

11

San Diego

1

12

12

Miami

1

13

13

Tampa Bay

1

14

14

Carolina

1

15

15

New Orleans

1

16

16

St. Louis

1

17

17

Pittsburgh

1

18

18

Dallas

1

19

19

New York Giants

1

20

20

Chicago

1

21

21

Cincinnati

1

22

22

St. Louis from Washington

1

23

23

Minnesota

1

24

24

Indianapolis

1

25

25

Seattle

1

26

26

Green Bay

1

27

27

Houston

1

28

28

Denver

1

29

29

New England

1

30

30

Atlanta

1

31

31

San Francisco

1

32

32

Baltimore

? ? ? ? ?

?

?

Round

Pick

Overall

2

1

33

Jacksonville

2

2

34

Kansas City

2

3

35

Philadelphia

2

4

36

Detroit

2

5

37

Cincinnati from Oakland

2

6

38

Arizona

2

7

?

Cleveland Exercised in Supplemental Draft

2

8

39

New York Jets

2

9

40

Tennessee

2

10

41

Buffalo

2

11

42

Miami

2

12

43

Tampa Bay

2

13

44

Carolina

2

14

?

New Orleans Forfeited

2

15

45

San Diego

2

16

46

St. Louis

2

17

47

Dallas

2

18

48

Pittsburgh

2

19

49

New York Giants

2

20

50

Chicago

2

21

51

Washington

2

22

52

Minnesota

2

23

53

Cincinnati

2

24

54

Miami from Indianapolis

2

25

55

Green Bay

2

26

56

Seattle

2

27

57

Houston

2

28

58

Denver

2

29

59

New England

2

30

60

Atlanta

2

31

61

San Francisco

2

32

62

Baltimore

? ? ? ? ?

?

?

Round

Pick

Overall

3

1

63

Kansas City

3

2

64

Jacksonville

3

3

65

Detroit

3

4

66

Oakland

3

5

67

Philadelphia

3

6

68

Cleveland

3

7

69

Arizona

3

8

70

Tennessee

3

9

71

Buffalo

3

10

72

New York Jets

3

11

73

Tampa Bay

3

12

74

San Francisco from Carolina

3

13

75

New Orleans

3

14

76

San Diego

3

15

77

Miami

3

16

78

St. Louis

3

17

79

Pittsburgh

3

18

80

Dallas

3

19

81

New York Giants

3

20

82

Miami from Chicago

3

21

83

Minnesota

3

22

84

Cincinnati

3

23

85

Washington

3

24

86

Indianapolis

3

25

87

Seattle

3

26

88

Green Bay

3

27

89

Houston

3

28

90

Denver

3

29

91

New England

3

30

92

Atlanta

3

31

93

San Francisco

3

32

94

Baltimore

?

?

Round

Pick

Overall

4

1

-

Jacksonville

4

2

-

Kansas City

4

3

-

Oakland

4

4

-

Philadelphia

4

5

-

Minnesota from Detroit

4

6

-

Arizona

4

7

-

Cleveland

4

8

-

Buffalo

4

9

-

New York Jets

4

10

-

Tennessee

4

11

-

Carolina

4

12

-

New Orleans

4

13

-

San Diego

4

14

-

Miami

4

15

-

Tampa Bay

4

16

-

St. Louis

4

17

-

Dallas

4

18

-

Pittsburgh

4

19

-

New York Giants

4

20

-

Chicago

4

21

-

Cincinnati

4

22

-

Washington

4

23

-

Minnesota

4

24

-

Indianapolis

4

25

-

Green Bay

4

26

-

Seattle

4

27

-

Houston

4

28

-

Denver

4

29

-

Tampa Bay from New England

4

30

-

Atlanta

4

31

-

San Francisco

4

32

-

Baltimore

?

?

Round

Pick

Overall

5

1

-

Kansas City

5

2

-

Jacksonville

5

3

-

Philadelphia

5

4

-

Detroit

5

5

-

Seattle from Oakland

5

6

-

Cleveland

5

7

-

Arizona

5

8

-

New York Jets

5

9

-

Tennessee

5

10

-

Buffalo

5

11

-

New Orleans

5

12

-

San Diego

5

13

-

Miami

5

14

-

Tampa Bay

5

15

-

Carolina

5

16

-

St. Louis

5

17

-

Pittsburgh

5

18

-

Dallas

5

19

-

New York Giants

5

20

-

Chicago

5

21

-

Washington

5

22

-

Minnesota

5

23

-

Cincinnati

5

24

-

San Francisco from Indianapolis

5

25

-

Seattle

5

26

-

Green Bay

5

27

-

Houston

5

28

-

Denver

5

29

-

Washington from New England

5

30

-

Atlanta

5

31

-

San Francisco

5

32

-

Baltimore

?

?

Round

Pick

Overall

6

1

-

Jacksonville

6

2

-

Kansas City

6

3

-

Detroit

6

4

-

Oakland

6

5

-

Cleveland from Philadelphia

6

6

-

Arizona

6

7

-

Cleveland

6

8

-

Arizona from Tennessee through Minnesota

6

9

-

Buffalo

6

10

-

New York Jets

6

11

-

San Diego

6

12

-

San Francisco from Miami

6

13

-

Tampa Bay

6

14

-

Carolina

6

15

-

New Orleans

6

16

-

St. Louis

6

17

-

Dallas

6

18

-

Pittsburgh

6

19

-

New York Giants

6

20

-

Chicago

6

21

-

Minnesota

6

22

-

Cincinnati

6

23

-

Washington

6

24

-

Indianapolis

6

25

-

Green Bay

6

26

-

Seattle

6

27

-

Houston

6

28

-

Philadelphia from Denver

6

29

-

Cincinnati from New England

6

30

-

Atlanta

6

31

-

San Francisco

6

32

-

Baltimore

?

?

Round

Pick

Overall

7

1

-

Kansas City

7

2

-

Jacksonville

7

3

-

Oakland

7

4

-

Philadelphia

7

5

-

Detroit

7

6

-

Philadelphia from Cleveland

7

7

-

Minnesota from Arizona

7

8

-

Seattle from Buffalo

7

9

-

New York Jets

7

10

-

Tennessee

7

11

-

Miami

7

12

-

Tampa Bay

7

13

-

Oakland from Carolina

7

14

-

Seattle from New Orleans

7

15

-

San Diego

7

16

-

St. Louis

7

17

-

Pittsburgh

7

18

-

Miami from Dallas

7

19

-

New York Giants

7

20

-

New England from Chicago through Tampa Bay

7

21

-

San Francisco from Cincinnati

7

22

-

Washington

7

23

-

Minnesota

7

24

-

Indianapolis

7

25

-

Seattle

7

26

-

Green Bay

7

27

-

Houston

7

28

-

Denver

7

29

-

New England

7

30

-

Atlanta

7

31

-

San Francisco

7

32

-

Baltimore

?

Source: http://www.wickedlocal.com/pro-sports-blogs/x2082697877/NFL-Draft-order-as-it-currently-stands?rssfeed=true

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All about medical tests

EXCHANGE SUPER SIZED HOSPITALSAP

For media purposes, the NFL Scouting Combine is a whirl of interviews and player availability.

For television watchers, the 40-yard dashes and drills take center stage.

But for the teams that come to Indianapolis to scout, the priority isn?t anything that happens on the field, but rather behind the scenes at the hospital.

The medical checks shared by 32 teams are the primary benefit for most teams.

National Football Scouting president Jeff Foster asked teams years ago to list their priorities, and the results were loud and clear.

?All 32 teams, medicals were No. 1,? Foster told Mike Chappell of the Indianapolis Star. ?All 32 teams, interviews were No. 2. Then there was a mix between the on-field stuff and the psychological testing.?

So for the seven-day duration, players are poked and prodded and tested and quizzed on their medical histories, with no detail to minute.

?This will be the most comprehensive exam they can ever hope to get,? said Dr. Arthur Rettig, one of the Colts team doctors. ?If possible, you want to save [a team] from investing a few million dollars in someone who may play one year and then he?s done.

?It?s our job to try and predict that.?

Retting said he expected to order up 350 MRI scans, using 17 machines they have on hand, including three mobile ones at Lucas Oil Stadium. In the past, they?ve found tumors in players while looking at other injuries.

Colts tackle Anthony Castonzo said he was amazed by the thoroughness of the process, going through six orthopedic stations, X-rays, MRIs, along with heart tests, baseline concussion tests and drug scans.

?You basically lay on a table in the middle of the room and you?ve got people coming over and poking and prodding on you, fiddling with your ankle or your knee or whatever it is you possibly had wrong,? Castonzo said. ?You kind of feel like a corpse at the morgue. Everyone is trying to figure out what?s wrong.?

For NFL teams trying to avoid investing millions in a bunch of stiffs, the process is worth it.

Source: http://profootballtalk.nbcsports.com/2013/02/21/for-nfl-teams-combine-is-all-about-the-medical-tests/related/

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Friday, February 22, 2013

New study shows how seals sleep with only half their brain at a time

Wednesday, February 20, 2013

A new study led by an international team of biologists has identified some of the brain chemicals that allow seals to sleep with half of their brain at a time.

The study was published this month in the Journal of Neuroscience and was headed by scientists at UCLA and the University of Toronto. It identified the chemical cues that allow the seal brain to remain half awake and asleep. Findings from this study may explain the biological mechanisms that enable the brain to remain alert during waking hours and go off-line during sleep.

"Seals do something biologically amazing ? they sleep with half their brain at a time. The left side of their brain can sleep while the right side stays awake. Seals sleep this way while they're in water, but they sleep like humans while on land. Our research may explain how this unique biological phenomenon happens" said Professor John Peever of the University of Toronto.

The study's first author, University of Toronto PhD student Jennifer Lapierre, made this discovery by measuring how different chemicals change in the sleeping and waking sides of the brain. She found that acetylcholine ? an important brain chemical ? was at low levels on the sleeping side of the brain but at high levels on the waking side. This finding suggests that acetylcholine may drive brain alertness on the side that is awake.

But, the study also showed that another important brain chemical ? serotonin - was present at the equal levels on both sides of the brain whether the seals were awake or asleep. This was a surprising finding because scientist long thought that serotonin was a chemical that causes brain arousal.

These findings have possible human health implications because "about 40% of North Americans suffer from sleep problems and understanding which brain chemicals function to keep us awake or asleep is a major scientific advance. It could help solve the mystery of how and why we sleep" says the study's senior author Jerome Siegel of UCLA's Brain Research Institute.

###

University of Toronto: http://www.utoronto.ca

Thanks to University of Toronto for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/126923/New_study_shows_how_seals_sleep_with_only_half_their_brain_at_a_time

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Thursday, February 21, 2013

Signaling pathway linked to fetal alcohol risk: Molecular switch promises new targets for diagnosis and therapy

Feb. 20, 2013 ? Fetal alcohol syndrome is the leading preventable cause of developmental disorders in developed countries. And fetal alcohol spectrum disorder (FASD), a range of alcohol-related birth defects that includes fetal alcohol syndrome, is thought to affect as many as 1 in 100 children born in the United States.

Any amount of alcohol consumed by the mother during pregnancy poses a risk of FASD, a condition that can include the distinct pattern of facial features and growth retardation associated with fetal alcohol syndrome as well as intellectual disabilities, speech and language delays, and poor social skills. But drinking can have radically different outcomes for different women and their babies. While twin studies have suggested a genetic component to susceptibility to FASD, researchers have had little success identifying who is at greatest risk or what genes are at play.

Research from Harvard Medical School and Veterans Affairs Boston Healthcare System sheds new light on this question, identifying for the first time a signaling pathway that might determine genetic susceptibility for the development of FASD. The study was published online Feb. 19 in the journal Proceedings of the National Academy of Sciences.

"Our work points to candidate genes for FASD susceptibility and identifies a path for the rational development of drugs that prevent ethanol neurotoxicity," said Michael Charness, chief of staff at VA Boston Healthcare System and HMS professor of neurology. "And importantly, identifying those mothers whose fetuses are most at risk could help providers better target intensive efforts at reducing drinking during pregnancy."

The discovery also solves a riddle that had intrigued Charness and other researchers for nearly two decades. In 1996, Charness and colleagues discovered that alcohol disrupted the work of a human protein critical to fetal neural development -- a major clue to the biological processes of FASD. The protein, L1, projects through the surface of a cell to help it adhere to its neighbors. When Charness and his team introduced the protein to a culture of mouse fibroblasts cells, L1 increased cell adhesion. Tellingly, the effect was erased in the presence of ethanol (beverage alcohol).

Charness and his team went on to develop multiple cell lines from that first culture, and that's where they encountered the riddle: In some of those lines, alcohol disrupted L1's adhesive effect, while in others it did not.

"How could it be possible that a cell that expresses L1 is completely sensitive to alcohol, and others that express it are completely insensitive?" asked Charness, who is also faculty associate dean for veterans hospital programs at HMS and assistant dean at Boston University School of Medicine.

Clearly, something else was affecting the protein's sensitivity to alcohol -- but what? Studies of twins provided one clue: Identical twins are more likely than fraternal twins to have the same diagnosis, positive or negative, for FASD. "That concordance suggests that there are modifying genes, susceptibility genes, that predispose to this condition," Charness said.

In the current study, Charness' team and collaborators at the University of North Carolina School of Medicine in Chapel Hill conducted cell culture experiments to identify specific molecular events that contribute to the alcohol sensitivity of L1 adhesion molecules. They focused on what was happening to the L1 molecule inside a cell that could affect an event outside the cell such as disruption by alcohol.

"We found that phosphorylation events that begin inside the cell can render the external portion of the L1 adhesion molecule more vulnerable to inhibition by alcohol," said Xiaowei Dou, HMS instructor in neurology in the Charness Lab and first author on the new study. "Phosphorylation was controlled by the enzyme ERK2, and occurred at a specific location on the internal portion of the L1molecule."

Phosphorylation plays a significant role in a wide range of cellular processes. By adding a phosphate group to a protein or other molecule, phosphorylation turns many protein enzymes on and off, and thereby alters their function and activity.

The researchers also found that variations in ERK2 activity correlated with differences in L1 sensitivity to alcohol that they observed across cell lines and among different strains of mice. "Dou showed that he could take these cells that had been insensitive to alcohol for 13-14 years, and make them sensitive by ramping up the activity of this kinase" Charness said.

These variations suggest that genes for ERK2 and the signaling molecules that regulate ERK2 activity might influence genetic susceptibility to FASD. Moreover, their identification of a specific locus that regulates the alcohol sensitivity of L1 might facilitate the rational design of drugs that block alcohol neurotoxicity.

"The only thing this modification blocked was alcohol's ability to inhibit L1," Charness said. "If you're looking for a drug, ideally you're looking for it to block the effects of the toxin without interfering with the target molecule of the toxin."

The findings will also help guide an international consortium in its search for genes linked to families with fetal alcohol spectrum disorders.

"Prenatal alcohol exposure is the leading preventable cause of birth defects and developmental disorders in the United States," said Kenneth Warren, acting director of the National Institute on Alcohol Abuse and Alcoholism (NIAAA),which supported the study. "These new findings are yet another important contribution from researchers who have been at the forefront of scientific discovery in FASD."

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Story Source:

The above story is reprinted from materials provided by Harvard Medical School. The original article was written by R. Alan Leo.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. X. Dou, M. F. Wilkemeyer, C. E. Menkari, S. E. Parnell, K. K. Sulik, M. E. Charness. Mitogen-activated protein kinase modulates ethanol inhibition of cell adhesion mediated by the L1 neural cell adhesion molecule. Proceedings of the National Academy of Sciences, 2013; DOI: 10.1073/pnas.1221386110

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/OGlPUkzo0MI/130220170736.htm

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Friday, February 15, 2013

Why Would all Organizations Care to Pay Me to Accomplish Online ...

Are you on the list of skeptics who doubt that paid online studies actually pay? Have you been contacted by individuals who are desperately trying to persuade you that doing paid reviews is a waste of time? Then you once for all be confident that finishing paid online surveys is value for your own time and effort, and definitely need to review your views on online surveys by reading the info obtainable in this article.

Companies giving settled web surveys have proliferated tremendously recently. Settled review offers are everywhere in the web space in pop-ups, backed links, and work-at-home sources. You get this type of large selection of survey offers it is understandable you might get confused to inform the legit survey offers from the cons. In fact, there?s a number of fraud sites that not spend earnings or mislead their subscribers in regards to the benefits of membership. However, you?ll find so many legitimate paid survey sites that provide results of web surveys at no cost.

Why would organizations bother to cover money to people for completing internet surveys? Even though it might appear too small a job to sit back at home and get some good $10-$20 an average of for five minutes of your time, paid internet surveys are now actually a billion-dollar business. Paid surveys have been acknowledged by companies as an effective and beneficial general market trends method, as only consumer surveys straight communicate useful customer ideas to the product suppliers. Settled studies are conceived to fundamentally help the merchandise and service industries develop and thrive, while worthwhile people with money and prizes for enough time spend sharing their honest thoughts.

Having such crucial issues at stake the survival and development of a number of small to large-scale companies, it?s now clearer why paid surveys are that important, and why it makes perfect business sense that customers get paid to accomplish surveys. It is true that as a survey taker may very well not get thousands yourself only by completing settled reviews in your free time. However, it?s quite possible that you might make great additional cash that will complement your mainstream income. While the average surveys payout is somewhere between $25 and $5, the highest-pay surveys can provide out as much as $200 for finishing more and longer specific questionnaires or taking part in focus groups. With 2-5 surveys each month by way of a single company, it also makes sense a subscription to as many study companies as you are able to. Like that, you increase your odds of getting more frequent invitations to perform paid reviews, and you get more stable profits.

Be wise enough to prevent the survey scams that are lurking out there, and trust only paid survey organizations that need no upfront investment from you. Some web sites providing online surveys demand membership as a means of funding their internet sites. However, its thoroughly possible to find out these same listings free of charge at other reliable, free paid review sites. Once youve realized that organizations are willing to pay good money for your client opinion, you should know that your participation as a survey taker makes substantial big difference to the entire world of advertising. Consequently, don?t shy away from your opportunity to lead your customer activities to the growing researching the market industry, while getting rewarded with good cash and rewards.

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Source: http://culturapopulara.ro/?p=20288

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'Harlem Shake' craze hits Eastern Michigan women's basketball team...and coach

Everyone seems to be getting in on the "Harlem Shake" craze. Include the Eastern Michigan women's basketball team among them.

The school uploaded a video of its players dancing to the popular song on Friday. Perhaps it was to stave off boredom during the team's bye week.

As is standard with the popular new dance craze, one individual is dancing all along while the entire Eagles team seems to be unaware or uninterested in what he is doing. But at the 15 second point of the video the entire team joins in.

With a football helmet and sunglasses on, the dance leader is unrecognizable, but a university spokesperson confirmed that it is first-year coach Tory Verdi leading the group.

Source: http://www.annarbor.com/sports/harlem-shake-craze-hits-eastern-michigan-womens-basketball-teamand-coach/?cmpid=RSS_link_sports

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