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Thursday, May 3, 2012
A Smart Garment With Life-Saving Implications [Design]
Ariana Grande: Dating Josh Hutcherson!
Josh Hutcherson is no longer hungering for a girlfriend. Why? Because he's reportedly playing the game of love with Ariana Grande!
An insider tells Life & Style that the actor is romantically involved with Victorious star Ariana Grande. She plays Cat Valentine on that Nickelodeon sitcom.
"They've been seeing each other since the beginning of the year," a source tells the tabloid, adding that Grande even attended the Los Angeles premiere of The Hunger Games with her man, but didn't walk down the red carpet because "they've been trying to keep it low-profile."
Hutcherson previously dated Vanessa Hudgens.
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Wednesday, May 2, 2012
Sofia Vergara, Breasts Cover GQ Mexico
In February, Sofia Vergara was voted the Most Desirable Woman in the World by readers of AskMen.com.
For those somehow questioning whether the Modern Family star is deserving of this honor, we present the cover of this month's GQ Mexico, along with a bra-less image of the beauty inside the magazine, and we say: Case. Closed.
Vergara is as well known for her breasts as she is for her acting - Jimmy Kimmel referenced the star's cleavage during his White House Correspondent's Dinner speech - but she doesn't seem to mind.
"My career is because of my look and I am not ashamed of it," Sofia tells GQ. "My look has opened so many doors. But I also know that if I had something else, my career would have ended long ago. That’s why I see Sophia Loren as the perfect example of beauty, sex appeal and how the one presented in public.”
Vergara adds that she takes "great satisfaction" from comparisons to much younger stars such as Megan Fox and Mila Kunis, while male readers will take great satisfaction from the following:
This Sofia Vergara nude photo.
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Chronicle of a trial foretold: Breivik is following his manifesto's script
Anders Behring Breivik's manifesto includes instructions on what a 'Templar' should do if tried in a European court.
Among the early headlines from the fourth day of the trial of Anders Behring Breivik for the murder of 77 people last July was that, for the first time, Mr. Breivik did not perform his now-familiar clenched-fist salute upon arrival at the court. Several families of Breivik's victims said they found the salute offensive, and his lawyers apparently were able to convince him to stop and avoid undermining his case.
Skip to next paragraphBut the drop of the salute is not only significant for its effect on his defense's strategy. It also marks a significant departure from Breivik's playbook: his 1,500-page manifesto. Breivik wrote extensively not only about his own beliefs about the alleged activities of "the Marxist tyrants of Europe" and the mission of the Knights Templar, or "Templars," the group to which he claims to belong. He also wrote a comprehensive set of instructions and guidelines for what a Templar should do if tried in a European court. He appears to be following it to the extent he is able.
Breivik wrote a short section on his salute, which he claims to be "the military salutation" of the Templars. He writes that the salute, which he recommends being performed in a white glove, symbolizes strength, purity, and resistance against "the Marxist tyrants of Europe." Interestingly, he claims the salute has nothing to do with either racist "white power" salutes or with the similar, open-palmed Nazi salute.
While Breivik's manifesto does not mention the salute specifically in reference to a trial, its use at trial fits closely into what Breivik argues is the best way to use trials: as propaganda. Breivik writes that after being captured, "the subsequent court proceedings may present several propaganda opportunities." He adds that "This trial is (from our point of view), not against you but rather a trial against the regime."
One of the key openings for propaganda that Breivik saw is the opportunity to present an opening and closing statement. Breivik includes a four-page sample opening statement, which he seemed to use as a source for his own.?
His sample draws parallels between the quest of the "Templars" and that of Native American leaders like Sitting Bull ? parallels he made on the first day of testimony in his own trial. As the Monitor reported, ?Were they terrorists for fighting for their indigenous culture ? or were they heroes?? Breivik asked the court. ?My acts are based on goodness, not evil,? he added. ?If anyone is vicious it is the Socialists.?
In the manifesto, Breivik also outlines a dress code for Templars, which he says should be adhered to in court. "Our dress uniform ... will be used for the sole?purpose of representing the authority of our military order and tribunal during trial," he writes. The uniform is to include a US Marine Corp dress jacket in dark blue or black, dress pants in the same color, and an extensive set of medals and decorations including epaulettes and Templar badges. Judging from the photos of his appearances in court, Breivik seems to have been following his own dress code as best he can, though he has appeared sans pseudo-military decorations.
In his game plan for Templar trial appearances, Breivik shows every expectation of losing. The heading for his sample closing statement reads: "Closing statement ? last day of trial, after judgment (guilty)." But he also expresses hope that the trial may lead to the introduction of stiffer criminal sentences, and perhaps even introduction of the death penalty, which is currently illegal in Norway.
The trial itself may not end up as anything else than a formality where the goal can be to change the law, forcing the parliament of that country to introduce the death penalty, or harshen the penal laws in other ways. Indirectly forcing the parliament of your country to change the laws will be an indirect victory to our movement because it will provide significant media coverage of our cause and thus will contribute to future recruitment efforts.
Breivik echoed this thinking during his second day of testimony, the Monitor reported.
?No, I don?t want [capital punishment], but I would have respected that,? he said, adding that if Norway doubled the current maximum sentence it would ?serve his cause? and ?prove Norway had thrown their principles out the window."
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Tuesday, May 1, 2012
Got Boondoggle?: Lean Snake Oil Cures what Ails Ya
Step right up Ladies and Gentleman! Do you suffer from bulging inventories? Are you feeling tired and wore down chasing problems everyday at work? Are parts of your organization afflicted by dislocation? Perhaps you suffer from irregularity of flow or constipation and blockage? Do rashes of quality problems create irritability and discomfort? Having trouble applying kanban or finding the time for kaizen? Do you find incorporating lean thinking into your culture just too difficult and painful?
My friends fear not! Your days of suffering are over. Just one bottle of this new and improved formula of lean elixir has been scientifically proven under the most rigorous of conditions to cure what ails ya!
Yes, you heard me correct, my dear friends. This wonderful tonic of the east has the magical like powers to create a self-healing, self-improving, self-regulating system to free you from the hard work, constant coaching and relentless pursuit of perfection. No need to lead by example or get your hands dirty understanding your processes or teach others within your organization. You no longer need to help improve, just let you employees do it on their own under this system of self fixing.
Taking regularly and by explicitly following the directions on the bottle, you will be transformed like never before. And for a few extra dollars, you can speed up the lean process like never before by adding heavy doses of metrics and measurements followed by holding them accountable. Now all you need to do is go back to your office, sit back, relax and let the miracle medicine work its wonder.
Who will be the first to free themselves from the burdens of continuous improvement? Step right up!
Doesn?t this spiel sound just like what you imagine a snake oil salesmen from yesteryear would bark to the crowd gathered around his traveling wagon of wonder cures and concoctions?
Today, there is plenty of snake oil to go around. There seems to be a lot of touting of different models to achieve higher levels of leanness. Some place emphasis on certain lean tools, others promote a specific path or model as the missing link to achieve lean greatness. Really, can a lean system be self healing and self improving? Seriously?
In all my years of experience in learning the lean way and applying lean thinking in various companies and industries, I found that there is no silver bullet and no one best way, despite the boisterous marketing hype. I also learned that lean systems do not run by themselves.
Using kaizen and developing lean thinking into your culture takes time, energy and effort. More time than you think, tons of energy and a tremendous amounts of effort. Even after all your blood, sweat and tears, there are still no guarantees.
The lean approach is not easy and requires practice, perseverance and patience. It takes serious commitment by management that most are not willing to make.
We need everyone involved in kaizen, everyday, everywhere. This certainly includes our management. Everyone needs to make time for kaizen. Management need to be in gemba more often, not less. Bottom line, you can?t delegate kaizen.
So next time you hear about some secret to becoming lean remember that hard work and personal commitment is no secret. In the wise words of our elders before us, ?if it sounds too good to be true, it is too good to be true?.
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Weird ocean current may create coral refuges
Global warming is expected to have devastating effects on coral reefs, but recent research points to a few exceptions.
Warming in the equatorial Pacific may actually create refuges for corals around a handful of islands, even as it bleaches, or kills, corals elsewhere, suggests new research that predicts increased upwelling of cold, nutrient-rich water in these places.
"These little islands in the middle of the ocean can counteract global trends and have a big impact on their own future, which I think is a beautiful concept," said study researcher Kristopher Karnauskas, a Woods Hole Oceanographic Institution scientist, in a press release issued by the institution.
If predictions made by Karnauskas and colleague Anne Cohen are accurate, warming around the Gilbert Islands will be slower than elsewhere, giving the corals and their symbiotic algae a better chance to adapt. Perhaps these refuges could eventually become a source of new corals and other species that could recolonize reefs damaged by warming, Karnauskas said.
Corals are animals that host tiny plants, or algae, that feed them using photosynthesis. The reefs corals build provide important habitat for many species. Warming water can cause corals to expel their algae, a phenomenon called bleaching, which turns the corals white and puts them under great stress and at risk of death. ?
Global climate models predict the central tropical Pacific will warm by about 5.0 degrees Fahrenheit by the end of the century. To get a better idea of how conditions might play out on a small geographic scale, the researchers used the global models in combination with a fine-scale regional model.
The low-lying coral atoll islands, part of the nation of Kiribati, are as small as 1.54 square miles.
As a result of other changes caused by warming, their work predicts the deep equatorial undercurrent (EUC), an eastward flowing current at the equator, will strengthen by 14 percent; this strengthening would create habitat for corals to flourish alongside the islands by bringing cooler water and nutrients to the surface. Though the EUC is an east-to-west current, when it hits an island, water gets deflected upward.
"Our model suggests that the amount of upwelling will actually increase by about 50 percent around these islands and reduce the rate of warming waters around them by about 1.25 degrees F per century," Karnauskas said.
The research appears in the April 30 issue of the journal Nature Climate Change.
You can follow LiveSciencesenior writer Wynne Parry on Twitter@Wynne_Parry. Follow LiveScience for the latest in science news and discoveries on Twitter @livescience and on Facebook.
? 2012 LiveScience.com. All rights reserved.
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MSU invention could help pharmaceutical industry save money
![[ Back to EurekAlert! ]](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_vh5BMReQkm26rXdY0EopeN3RsXvNxwjE1jNGEWP1L9F9ArAGQdBmVlbeaOhd6JJGFZ-ZJtN423_ZTXdPUIfQ5Jce45VwsvJ4dz3afj0rk=s0-d){kind=small}
Public release date: 30-Apr-2012[ | E-mail |
Share ] Contact: Layne Cameron
layne.cameron@ur.msu.edu
517-353-8819
Michigan State University
EAST LANSING, Mich. Two Michigan State University researchers have invented a protein purifier that could help pharmaceutical companies save time and money.
The details of the invention, which appear in a recent issue of the journal Langmuir, demonstrate that MSU chemists Merlin Bruening and Greg Baker's high-performance membranes are highly suitable for protein purification, a crucial step in the development of some new drugs.
Purifying proteins, the process of isolating a single, desired protein from all others, is an expensive, time-consuming hurdle that contributes to the high cost of some prescription drugs. Obtaining pure proteins, however, is a necessary step to increasing these drugs' effectiveness and safety. Streamlining the process could help manufacturers reduce costs, speed new drugs to consumers and reduce pharmaceutical costs, Bruening said.
"The membrane devices that we've manufactured can simplify protein purification by rapidly capturing the desired protein as it flows through membrane pores," said Bruening, who has patented the process and is working to scale up his invention. "Our membranes have two to three times more capacity than existing commercial devices, and they should reduce the purification process time substantially. Typically, our procedures are complete in 30 minutes or less."
The pursuit of a comparable, but complex purification procedure led to the discovery of the researchers' simpler invention. Bruening and his colleague were trying to grow extended polymer chains in the membranes in a multistep, oxygen-free process. Untangling the complexities of the first method led to the revelation that direct adsorption of acidic polymers at low pH is much simpler yet accomplishes the same task of creating extended polymer in the pores. (The purifier uses adsorption rather than absorption; the filter attracts contaminants to its surface rather than sucks them up like a sponge.)
"Once our findings began steering us toward the simpler solution, we began developing simple processes to modify membranes by simply flowing polymer solutions through the membranes," Bruening said.
The next challenge for Bruening and his colleagues will be to upscale his invention so that rapid protein purification with inexpensive membranes becomes a standard for not only pharmaceutical companies, but also researchers trying to rapidly isolate proteins to determine their structure and function.
###
Fellow MSU chemists Baker, Somnath Bhattacharjee, Jinlan Dong, Yiding Ma, Stacy Hovde and James Geiger and contributed to the paper.
Michigan State University has been working to advance the common good in uncommon ways for more than 150 years. One of the top research universities in the world, MSU focuses its vast resources on creating solutions to some of the world's most pressing challenges, while providing life-changing opportunities to a diverse and inclusive academic community through more than 200 programs of study in 17 degree-granting colleges.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 30-Apr-2012[ | E-mail |
Share ] Contact: Layne Cameron
layne.cameron@ur.msu.edu
517-353-8819
Michigan State University
EAST LANSING, Mich. Two Michigan State University researchers have invented a protein purifier that could help pharmaceutical companies save time and money.
The details of the invention, which appear in a recent issue of the journal Langmuir, demonstrate that MSU chemists Merlin Bruening and Greg Baker's high-performance membranes are highly suitable for protein purification, a crucial step in the development of some new drugs.
Purifying proteins, the process of isolating a single, desired protein from all others, is an expensive, time-consuming hurdle that contributes to the high cost of some prescription drugs. Obtaining pure proteins, however, is a necessary step to increasing these drugs' effectiveness and safety. Streamlining the process could help manufacturers reduce costs, speed new drugs to consumers and reduce pharmaceutical costs, Bruening said.
"The membrane devices that we've manufactured can simplify protein purification by rapidly capturing the desired protein as it flows through membrane pores," said Bruening, who has patented the process and is working to scale up his invention. "Our membranes have two to three times more capacity than existing commercial devices, and they should reduce the purification process time substantially. Typically, our procedures are complete in 30 minutes or less."
The pursuit of a comparable, but complex purification procedure led to the discovery of the researchers' simpler invention. Bruening and his colleague were trying to grow extended polymer chains in the membranes in a multistep, oxygen-free process. Untangling the complexities of the first method led to the revelation that direct adsorption of acidic polymers at low pH is much simpler yet accomplishes the same task of creating extended polymer in the pores. (The purifier uses adsorption rather than absorption; the filter attracts contaminants to its surface rather than sucks them up like a sponge.)
"Once our findings began steering us toward the simpler solution, we began developing simple processes to modify membranes by simply flowing polymer solutions through the membranes," Bruening said.
The next challenge for Bruening and his colleagues will be to upscale his invention so that rapid protein purification with inexpensive membranes becomes a standard for not only pharmaceutical companies, but also researchers trying to rapidly isolate proteins to determine their structure and function.
###
Fellow MSU chemists Baker, Somnath Bhattacharjee, Jinlan Dong, Yiding Ma, Stacy Hovde and James Geiger and contributed to the paper.
Michigan State University has been working to advance the common good in uncommon ways for more than 150 years. One of the top research universities in the world, MSU focuses its vast resources on creating solutions to some of the world's most pressing challenges, while providing life-changing opportunities to a diverse and inclusive academic community through more than 200 programs of study in 17 degree-granting colleges.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
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